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芍药二酮具强抑制人体单核白细胞介素-1β活性以抑制与烟酚胺腺嘌呤二核苷酸磷酸(NADPH)联结的3α-羟类固醇脱氢酶(3α-HSD)的活性为指导进行分离,得到一个很好的抑制3α-HSD活性的新三萜——芍药二酮(palbinone),发现该化合物可以显...
Paeonol diketone strongly inhibits the activity of human mononuclear interleukin-1β and inhibits the activity of 3α-hydroxysteroid dehydrogenase (3α-HSD) linked to nicotinamide adenine dinucleotide phosphate (NADPH). Separated to get a good inhibition of 3α-HSD activity of the new triterpenoid - palindone (palbinone), found that the compound can be ...