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目的探讨真菌败血症发病原因和临床特点病原菌情况,探讨其防治措施。方法对2014年3月至2016年3月邢台市第三医院新生儿重症监护病房7例真菌败血症的临床资料进行回顾性分析。结果 /结论 (1)早产、低出生体重儿、长期使用广谱抗生素、激素及静脉营养,长期留置中心静脉导管及气管插管为真菌败血症的高危因素。(2)病原学检查均为白色念珠菌。(3)给予静脉应用氟康唑治疗后有效,而且早期应用氟康唑治疗效果好。
Objective To investigate the pathogenesis of fungal sepsis and clinical characteristics of pathogens, to explore its prevention and treatment. Methods The clinical data of 7 cases of fungal sepsis in neonatal intensive care unit in the Third Hospital of Xingtai from March 2014 to March 2016 were analyzed retrospectively. RESULTS / CONCLUSIONS (1) Premature delivery and low birth weight infants, long-term use of broad-spectrum antibiotics, hormones and intravenous nutrition, long-term indwelling central venous catheter and tracheal intubation are risk factors for fungal septicemia. (2) pathogenic tests are Candida albicans. (3) given intravenous fluconazole treatment effective, and the early application of fluconazole treatment effect.