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小檗属植物(通称三颗针)的根是提取盐酸小檗碱的原料。小檗碱以盐酸盐的形式存在于植物体内,该盐难溶于水,为增加其溶解度,可与硫酸等二元酸及二元酸以上的酸生成盐后提取。本文就盐酸小檗碱的提取条件作了实验比较,报道如下。提取盐酸小檗碱粗品时,酸、时间及盐的实验比较1.原料:以滇产土黄连(即三颗针)的根为原料,经自然风干,磨粉过6目筛即得(药厂生
The root of Berberis (commonly known as three needles) is the raw material for berberine hydrochloride extraction. Berberine is present in the plant as a hydrochloride salt. The salt is hardly soluble in water. To increase its solubility, it can be extracted with a dibasic acid such as sulfuric acid, or a dibasic acid or higher. In this paper, the experimental conditions for the extraction of berberine hydrochloride were compared and reported as follows. For the extraction of crude berberine hydrochloride, the comparison of acid, time, and salt was performed. 1. Raw materials: The roots of Coptis chinensis (three needles) were used as the raw materials, and they were naturally air-dried and ground through a 6-mesh sieve. Factory students