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本发明提供一种醛与硝基烯烃的加成产物的制备方法,以(S)-脯氨酸锂或(R)-脯氨酸锂作为手性催化剂,催化醛与硝基烯烃的不对称Michael加成反应,所述(S)-脯氨酸锂或(R)-脯氨酸锂不仅催化
The present invention provides a method for preparing an addition product of an aldehyde and a nitroolefin by catalyzing the asymmetry between the aldehyde and the nitroolefin by using lithium (S) -proline or lithium (R) -proline as a chiral catalyst Michael addition reaction, the (S) -proline lithium or (R) -proline lithium not only catalyses