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本文报道2例急性白血病的细胞形态学变异。均是急性淋巴细胞白血病(ALL)转化为急性粒细胞白血病(AML)。 一、病例报告 例1,女,28岁,干部,因头昏、乏力、纳差、牙龈出血4月,于1983年4月5日入院,体检无明显体征;骨髓增生极度活跃,粒、红系均受抑;原淋5%、幼淋48%;幼稚淋巴细胞形态不规则,部分细胞有伪足样突起;细胞化学染色:过氧化酶(一),糖元(+)。诊断ALL(L_1)。经VAMP(长春新碱、氨甲喋呤、6巯嘌呤、强地松)等方案治疗达到完全缓解,半年内先后骨穿7次,均为ALL(L_1)。1983年10月反复高热、鼻
This article reports two cases of acute leukemia cell morphological variation. All are acute lymphoblastic leukemia (ALL) into acute myeloid leukemia (AML). Case report 1, female, 28 years old, cadre, due to dizziness, fatigue, anorexia, bleeding gums in April, was admitted on April 5, 1983, no obvious physical examination; bone marrow hyperplasia extremely active, grain, red Were inhibited; the original leaching 5%, young leaching 48%; immature lymphocytes irregular shape, some cells have pseudopodia Protuberance; cytochemical staining: peroxidase (A), glycogen (+). Diagnosis ALL (L_1). After VAMP (vincristine, methotrexate, 6 mercaptopurine, prednisone) and other programs to achieve complete remission, within six months had bone wear seven times, are ALL (L_1). October 1983 repeated high fever, nose