Severe vulgaris psoriatic patients with acute myelogenous leukaemia and resolution after allogeneic

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Psoriasis is a common disease with a prevalence of up to 2% in the world population.1 The pathophysiological mechanism of this inflammatory disease has not been determined although it is generally accepted to have a genetic predisposition and be T-cell mediated. The lymphocytes are the target of psoriatic therapeutic strategies. Therapy resolves psoriasis for a time, but induces some severe side effects. Some cases of severe psoriasis, treated with multiple therapeutic regimens for many years, developed leukemia.
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