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目的:分析免疫球蛋白(Ig)水平和超敏C反应蛋白(hs-CRP)水平在小儿早期手足口病中的临床诊断价值。方法:收集该院2013年1月至2015年12月间接诊的患手足口病的200例患儿进行临床研究,并将其作为研究组;同时选取同期于我院进行健康体检的200例健康儿童作为对照组进行对照研究。分别对两组儿童的Ig水平与hs-CRP水平进行检测,并进行比较分析。结果:研究组患儿的IgA水平为(0.59±0.33)g/L,明显低于对照组的(1.16±0.69)g/L;研究组患儿的IgG水平为(7.84±2.56)g/L,明显低于对照组儿童的(9.21±2.60)g/L;研究组患儿的IgM水平为(2.18±0.35)g/L,明显高于对照组儿童的(1.25±0.30)g/L;研究组患儿的hs-CRP水平为(5.81±2.13)mg/L,明显高于对照组儿童的hs-CRP水平[(25.014 2)mg/L,P<0.05]。结论:Ig与hs-CRP水平检测在早期小儿手足口病的临床诊断中具有良好的应用价值。
Objective: To analyze the clinical diagnostic value of immunoglobulin (Ig) level and high-sensitivity C-reactive protein (hs-CRP) levels in early hand-foot-mouth disease in children. Methods: A total of 200 children with hand-foot-mouth disease admitted from January 2013 to December 2015 in our hospital were enrolled in this study. The 200 cases were selected as study group. At the same time, 200 healthy people Children as a control group for control study. The levels of Ig and hs-CRP in the two groups of children were detected and compared. Results: The level of IgA in the study group was (0.59 ± 0.33) g / L, which was significantly lower than that in the control group (1.16 ± 0.69) g / L. The IgG level in the study group was (7.84 ± 2.56) g / L (9.21 ± 2.60) g / L in the control group. The IgM level in the study group was (2.18 ± 0.35) g / L, which was significantly higher than that in the control group (1.25 ± 0.30) g / L. The level of hs-CRP in the study group was (5.81 ± 2.13) mg / L, which was significantly higher than that of the control group [(25.014 2) mg / L, P <0.05]. Conclusion: The detection of Ig and hs-CRP has a good value in the clinical diagnosis of hand-foot-mouth disease in infants.