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目的了解梅毒感染孕产妇性伴梅毒检测情况,探讨相关影响因素,为广东省预防梅毒母婴传播项目工作持续改进提供参考依据。方法常规收集2013年广东省各级助产机构发现并上报的梅毒感染孕产妇资料,通过国家预防艾滋病、梅毒和乙肝母婴传播管理信息系统报告并收集相关数据,运用χ~2检验和多因素Logistic回归分析梅毒感染孕产妇性伴接受检测情况和感染状况的影响因素。结果共计1476例梅毒感染孕产妇及其性伴纳入本次研究。仅获得25.3%的感染孕产妇性伴梅毒感染资料,性伴梅毒感染率为24.7%。与21~35岁年龄组孕产妇相比,≥36岁年龄组孕产妇性伴梅毒感染状态得到明确诊断的可能性小(调整OR=0.61,95%CI:0.43~0.88);同教育程度不详的感染孕产妇相比,孕产妇学历明确其性伴接受梅毒检测的可能性大,且教育程度在大学及以上者性伴接受梅毒检测情况的可能性最大(调整OR=5.97,95%CI:2.51~14.19);感染孕产妇既往有感染史者,其性伴接受检测的可能性大(调整OR=1.92,95%CI:1.47~2.51);与孕早期诊断相比,孕产妇梅毒诊断时期越晚其性伴接受梅毒检测的可能性也越小,且产后及其他时期诊断者性伴接受梅毒检测的可能性最小(调整OR=0.36,95%CI:0.21~0.63);与性传播相比,孕产妇感染途径不详或其他,其性伴梅毒感染可能性小(调整OR=0.25,95%CI:0.16~0.42)。结论广东省梅毒感染孕产妇性伴梅毒检测率较低,应重点加强对高龄孕产妇、教育程度较低孕产妇及其性伴梅毒检测意义的宣传教育,促进孕产妇及其性伴主动筛查治疗,避免孕产妇梅毒反复感染对胎婴儿的危害。
Objective To understand the detection of syphilis among pregnant women with syphilis infection and to explore the related influencing factors so as to provide a reference for the continuous improvement of prevention of mother-to-child transmission of syphilis in Guangdong Province. Methods The pregnant women with syphilis infection detected and reported by the midwifery institutions at all levels of Guangdong Province in 2013 were routinely collected. Relevant data were collected through the national AIDS prevention, syphilis and hepatitis B mother-to-infant transmission management information system, and theχ ~ 2 test and multiple factors Logistic Regression Analysis of Influencing Factors of Pregnancy Companionship and Infection Status of Syphilis Infection. Results A total of 1476 cases of syphilis infection in pregnant women and their sexual partners included in this study. Only 25.3% of infected pregnant women with syphilis infection data, sexual partner syphilis infection rate was 24.7%. Compared with pregnant women in the 21-35 age group, the incidence of syphilis among pregnant women ≥36 years of age was less likely to have a definite diagnosis (adjusted OR = 0.61, 95% CI: 0.43-0.88); the same level of education (Adjusted OR = 5.97, 95% CI: 9), and the probability of receiving syphilis was significantly higher in males with maternal qualifications than with syphilis, 2.51 ~ 14.19). Infection of pregnant women with previous history of infection, the possibility of their partners being tested (adjusted OR = 1.92,95% CI: 1.47 ~ 2.51); compared with the first trimester diagnosis, maternal syphilis diagnosis The later the sex partners are less likely to receive syphilis, the less likely they are to undergo syphilis testing (adjusted OR = 0.36, 95% CI: 0.21-0.63) for post-natal and other diagnostic partners; The maternal infection was less known or more likely than the other, with a low likelihood of sexual partner syphilis infection (adjusted OR = 0.25, 95% CI: 0.16 to 0.42). Conclusions There is a low detection rate of syphilis among pregnant women with syphilis infection in Guangdong Province. Publicity and education should be focused on detection of senile pregnant women, low education level pregnant women and their partner syphilis, and to promote the active screening of pregnant women and their sexual partners Treatment, to avoid repeated maternal infection of syphilis on the baby’s harm.