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概论1827年英国医师Richard Brisht 氏发现一种病人:他们具有动脉血压升高,心臓增大,浮肿及蛋白尿,死后肾臓有组织学的改变;以后对于许多具备某些相同症状的肾臓双侧弥漫性进行性非化膿性疾患,统称之为孛来氏病(Brights disease)。实际上本病中包括许多不同病因,不同发病机制及不同予后的肾臓疾患;但尿中出现蛋白,红血球,圆柱,血压增高,浮肿,氮质潴留或尿毒症不为某种疾病所特有,系多种肾臓疾病所共
Introduction In 1827 British physician Richard Brisht’s found a patient who had elevated arterial blood pressure, enlarged heart, edema, and proteinuria, and had histological changes in the nephrogram after death; and later on for many nephrons with some of the same symptoms Bilateral diffuse progressive non-purulent disease, collectively referred to as Brig disease (Brights disease). In fact, the disease includes many different etiology, different pathogenesis and different to the post-nephrotic disease; but urine protein, red blood cells, cylinders, blood pressure, edema, nitrogen retention or uremia is not unique to a disease , Department of a variety of kidney disease total