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大鼠实验性肠梗阻时,肠粘膜组胺含量较对照组显著降低,但对血中组胺含量无明显影响。大承气汤、芍甘汤(10g/kg)灌胃给药,大黄素(100mg/kg),番泻甙(50mg/kg)腹腔注射,均可使肠梗阻大鼠肠粘膜组胺含量恢复至正常水平。
In rats with experimental intestinal obstruction, the content of histamine in the intestinal mucosa was significantly lower than that in the control group, but there was no significant effect on the content of histamine in the blood. Dachengqi Decoction and Decoction (10g/kg) were intragastrically administered, emodin (100mg/kg), and senna (50mg/kg) were injected intraperitoneally, both of which can restore the content of histamine in intestinal mucosa of intestinal obstruction rats. To normal level.