论文部分内容阅读
鼻息肉,阿斯匹林过敏和支气管哮喘合称为“阿斯匹林、哮喘三联症”(简称 ASA 三联症)。对阿斯匹林可诱发哮喘的认识至今已有七十多年的历史。1911年 Gilbert 首次报告了阿斯匹林能引起支气管哮喘,以后又发现其他许多阿斯匹林样作用的非激素类解热镇痛剂也能引起哮喘的发作,故又有“解热镇痛剂过敏性哮喘”之称。此外某些人造染料(如四嗪黄)、食品香料和药物佐剂也有交叉过敏反应,故本病的促发物质相当广泛,且此病在哮喘病人中所占比例不小。目前对其发病机制逐渐有所了解,本文就该病的有关问题作一概述。
Nasal polyps, aspirin allergy and bronchial asthma collectively known as “aspirin, asthma triad” (referred to as ASA triad). The awareness of aspirin-induced asthma has been more than seventy years old. Gilbert for the first time in 1911 reported that aspirin can cause bronchial asthma, and later found that many other aspirin-like non-hormonal antipyretic analgesics can also cause asthma attacks, it has “antipyretic analgesia Agent allergic asthma, ”said. In addition, some artificial dyes (such as tetrazine yellow), food spices and pharmaceutical adjuvant also have cross-allergic reactions, so the disease caused by a wide range of substances, and the disease in the proportion of asthma patients is not small. The pathogenesis of the current gradually understand, this article on the disease to make an overview of the issues.