A Novel Fluorescent Probe for ATP Detection Based on Synergetic Effect of Aggregation-induced Emissi

• 作 者: PAN Quan MA Feiyan PU Xinqing ZHAO Manyi WU Qiling ZHAO Na YANG Jun TANG Ben Zhong
• 机 构: Key Laboratory of Macromolecular Science of Shaanxi Province,School of Chemistry & Chemical Engineer
• 出 处: 高等学校化学研究（英文版）
• 发表日期: 2021年1期
• 关键词: Fluorescent probe Adenosine triphosphate Aggrega-tion-induced emission Counterio

In this work,a fluorescent probe(TPEBe-I)was developed for adenosine triphosphate(ATP)detection based on the synergetic effect of aggregation-induced emission and counterion displace-displacement.TPEBe-I gave weak emission in aqueous solution due to the heavy-atom effect of counter iodide ion. However, upon the addition of ATP, the new aggregate complex(TPEBe-ATP) was formed between the cationic unit of TPEBe-I and ATP through electrostatic interactions,which not only restricted the intramolecular motion of luminogen but also eliminated the quenching effect of iodide ion. As a result, the fluorescent light-up detection for ATP was successfully achieved. Moreover, TPEBe-I exhibited high selectivity towards ATP and showed a wide linear detection region towards the logarithm of ATP concentration(5-600 μmol/L) with a detection limit of 1.0μmol/L, enabling TPEBe-I as a promising probe for ATP quantitative analysis.