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目的探讨新辅助化疗在宫颈癌治疗中的效果。方法对86例宫颈癌Ⅰb~Ⅱb期女性患者采用全身化疗,用TP方案(紫杉醇+卡铂),每3~4周1次,共用1~3个疗程。结果 86例中44例宫颈病灶明显缩小50%占51%,24例宫颈病灶几乎完全消失占28%,病情稳定无进展18例占21%。结论新辅助化疗可提高Ib~IIb期宫颈癌的手术成功率,延长患者的生存期。
Objective To investigate the effect of neoadjuvant chemotherapy in the treatment of cervical cancer. Methods Totally 86 patients with stage Ⅰb ~ Ⅱb cervical cancer were treated with systemic chemotherapy with TP regimen (paclitaxel + carboplatin) once every 3 ~ 4 weeks for 1 ~ 3 cycles. Results Among the 86 cases, 44 cases of cervical lesions were significantly reduced by 50% and 51%, 24 cases of cervical lesions disappeared almost completely, 28% and 18 cases were stable and no progress, accounting for 21%. Conclusion Neoadjuvant chemotherapy can improve the success rate of Ib ~ IIb cervical cancer surgery, prolong the survival of patients.