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目的分析获得性风疹患者并肝功能损害临床特点,为临床诊治及判断预后提供依据。方法收集57例获得性风疹并肝功能损害患者,记录分析相关资料。结果获得性风疹患者并发肝功能损害发生率高达54.3%,但肝功能损害多轻微,多数出现在病程的5~7 d内。并发肝功能损害患者组平均住院16.7 d,与无并发症患者组平均住院日7.1 d比较,差异有统计学意义(t=6.03,P<0.05)。结论获得性风疹患者并发肝功能损害发生率高,明显延长病程及住院时间,但多数肝功能改变轻微,恢复较快,预后较好。
Objective To analyze clinical features of acquired rubella in patients with liver dysfunction and provide evidence for clinical diagnosis and prognosis. Methods Fifty-seven patients with acquired rubella and liver dysfunction were collected and the relevant data were recorded and analyzed. Results The incidence of liver dysfunction in acquired rubella patients was as high as 54.3%. However, the damage to liver function was mild and mostly occurred within 5 to 7 days of the course of disease. The mean hospital stay was 16.7 days in patients with liver dysfunction, compared with 7.1 days in patients without complications. The difference was statistically significant (t = 6.03, P <0.05). Conclusions The incidence of liver dysfunction in acquired rubella patients is high, which obviously prolongs the course of disease and hospital stay. However, most of the liver function changes slightly, resumes fast and the prognosis is good.