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对四川北部地区食管癌家族性1:1病例一对照资料进行分析表明,川北地区食管癌发病有明显的家族高发现象,血缘关系与食管癌的发病有显著联系,共同生活作用不显著,血缘关系与共同生活存在交互作用,其加权遗传度为18.95％。虽然目前关于内外环境因素在食管癌发病中的作用还存在争议,但我们初步认为,食管癌不是由遗传或后天共同生活因素独立作用的结果,而是二者长期相互作用的产物,其遗传素质所决定
A case-control study of familial 1: 1 esophageal cancer in the northern part of Sichuan showed that the incidence of esophageal cancer in northern Sichuan was significantly higher than that of esophageal cancer. There was a significant association between blood relationship and the incidence of esophageal cancer, with no significant effect on common life, There is interaction with common life, the weighted genetic degree is 18.95%. Although the role of internal and external environmental factors in the pathogenesis of esophageal cancer is still controversial, we initially believe that esophageal cancer is not a result of the independent interaction between heredity and acquired life, but the product of long-term interaction between the two. The genetic quality Decided