Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells

• 作 者: Kuo-ChingYang Yih-HueiUen Fat-
• 机 构: DepartmentofInternalMedicine,DepartmentofInternalMedicine,DepartmentofSurgery,DepartmentofInternalMe
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2005年20期
• 关键词: 分子机制 结肠肿瘤 肿瘤细胞 药物诱导 抗肿瘤药 Denbinobin Colon cancer Nude mice Apoptosis ERK pat
• 基金项目: the Shin Kong Wu Ho-Su Memorial Hospital，the Chi Mei Medical Center

AIM: To explore both the in vitro and in vivo effects of denbinobin against colon cancer cells and clarify its underlying signal pathways.METHODS: We used COLO 205 cancer cell lines and nude mice xenograft model to study the in vitro and in vivo anti-canc