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心内膜单相动作电位研究表明,单相动作电位的复极进程能够正确反映心肌细胞动作电位复极时程。狗静脉注射氯化铯后早期后除极电位(EAD)的发生率为100％,单相动作电位90％复极时程明显延长(224.4±50.6ms VS 368.4±34ms),与QT间期延长相一致。氯化铯诱发的室性心律失常发生于EAD顶峰,触发心律联律间期与EAD联律间期密切相关。硫酸镁使EAD和室性心律失常同时消失。提示该心律失常为EAD触发活性所致。
Endocardial single-phase action potential studies have shown that single-phase action potential repolarization process can correctly reflect the cardiomyocyte action potential repolarization duration. After intravenous injection of cesium chloride in dogs, the incidence of EAD was 100% and the duration of 90% single-phase action potential prolonged significantly (224.4 ± 50.6 ms VS 368.4 ± 34 ms), prolonging the QT interval Consistent. Cesium chloride-induced ventricular arrhythmias occur at the peak of EAD, triggering the intercourse of cardioversion is closely related to the EAD intercourse interval. Magnesium sulfate disappeared simultaneously with EAD and ventricular arrhythmias. Suggesting that the arrhythmia is caused by EAD triggering activity.