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目的分析氮卓斯汀鼻喷剂与地氯雷他定并用治疗过敏性鼻炎的疗效。方法采用随机法将潮州市中心医院2014年3月-2016年3月期间收治的84例过敏性鼻炎患者作为本次研究对象,并将其分为对照组与观察组各42例。对照组采用氮唑斯汀鼻喷剂对患者进行治疗,观察组采用氮卓斯汀鼻喷剂联合地氯雷他定对患者进行治疗。将两组患者的临床治疗效果、并发症发生率以及症状评分进行对比。结果对照组治疗总有效率为71.43%,明显低于观察组的92.86%,差异有统计学意义(χ~2=6.57,P<0.05);对照组不良反应发生率为23.81%高于观察组的7.14%,差异有统计学意义(χ~2=4.46,P<0.05);对照组治疗后的各项症状评分均明显高于观察组,差异有统计学意义(P<0.05)。结论过敏性鼻炎的最佳治疗方案是将氮卓斯汀鼻喷剂与地氯雷他定进行联合使用,该方法不仅具有较高的疗效、安全性,而且还能够明显降低患者的症状评分,值得推广。
Objective To analyze the curative effect of azelastine nasal spray combined with desloratadine in the treatment of allergic rhinitis. Methods Eighty-four patients with allergic rhinitis admitted from March 2014 to March 2016 in Chaozhou Central Hospital were randomly divided into control group and observation group, with 42 cases in each group. The patients in the control group were treated with nitazoxanide nasal spray and the patients in the observation group were treated with nitroglycerin nasal spray and desloratadine. The clinical outcomes, complication rates, and symptom scores were compared between the two groups. Results The total effective rate of the control group was 71.43%, which was significantly lower than that of the observation group (92.86%), the difference was statistically significant (χ ~ 2 = 6.57, P <0.05). The incidence of adverse reactions in the control group was 23.81% The difference was statistically significant (χ ~ 2 = 4.46, P <0.05). The symptom score of the control group after treatment was significantly higher than that of the observation group (P <0.05). Conclusion The best treatment for allergic rhinitis is the combined use of azelastine nasal spray and desloratadine. This method not only has high efficacy and safety, but also can significantly reduce the patient’s symptom score, Worth promoting.