论文部分内容阅读
目的了解西部某国企员工血尿酸水平及高尿酸血症与心血管病危险因素的关联性。方法采用横断面调查的方法,对西部某国企参加体检的员工进行调查。调查内容包括问卷调查、体格检查以及生化指标测定。结果共调查4 180名员工,高尿酸血症患病率为16.6%。高尿酸血症患者与非高尿酸血症患者的体重指数(BMI)、收缩压、舒张压、总胆固醇、甘油三酯、空腹血糖及男性所占比例、吸烟者所占比例之间的差异存在统计学意义(P<0.05)。多元线性回归分析显示,性别、BMI、收缩压、总胆固醇与血尿酸水平存在正相关,年龄与血尿酸水平存在负相关,差异有统计学意义(P<0.05)。非条件logistic回归分析显示,年龄、性别、BMI值、血压值、总胆固醇、空腹血糖水平与高尿酸血症密切相关(P<0.05),男性、高BMI值、血压值偏高、高胆固醇是高尿酸血症的危险因素;年龄增长、高血糖是高尿酸血症的保护性因素。结论高尿酸血症与心血管病危险因素密切相关。
Objective To understand the relationship between serum uric acid level and the risk of hyperuricemia and cardiovascular disease among workers in a state-owned enterprise in the west of China. Methods The method of cross-sectional survey was used to investigate the employees participating in the physical examination in a state-owned enterprise in the west. Survey includes questionnaires, physical examination and biochemical determination. Results A total of 4 180 employees were surveyed. The prevalence of hyperuricemia was 16.6%. Body mass index (BMI), systolic blood pressure, diastolic blood pressure, total cholesterol, triglycerides, fasting blood glucose and the proportion of men, the proportion of smokers in patients with hyperuricemia and non-hyperuricemia exist Statistical significance (P <0.05). Multivariate linear regression analysis showed that there was a positive correlation between gender, BMI, systolic blood pressure, total cholesterol and serum uric acid level. There was a negative correlation between age and blood uric acid level (P <0.05). Non-conditional logistic regression analysis showed that age, sex, BMI, blood pressure, total cholesterol and fasting blood glucose levels were closely related to hyperuricemia (P <0.05). Men with high BMI, high blood pressure and high cholesterol Hyperuricemia risk factors; age, hyperglycemia is a protective factor of hyperuricemia. Conclusion Hyperuricemia is closely related to the risk factors of cardiovascular disease.