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已有人报告过系统性硬皮病(SSc)患者血清Ⅲ型原胶原氨基末端前肽(P3NP)水平升高,但正常皮肤和硬皮病皮肤中主要胶原成分是Ⅰ型胶原。因此作者研究了SSc患者中血清Ⅰ型原胶原羧基末端前肽(P_1CP)水平,以了解后者与临床特征间的关系。血标本采自61例SSc患
It has been reported in patients with systemic scleroderma (SSc) serum levels of type III procollagen amino terminal propeptide (P3NP) levels increased, but the normal skin and scleroderma skin collagen is the main type collagen. The authors therefore investigated the serum level of procollagen carboxy-terminal propeptide (P-1CP) in patients with SSc to understand the relationship between the latter and clinical features. Blood samples were collected from 61 SSc patients