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STAT3,STAT5的异常表达和活化,与肿瘤的发生、发展及恶性生物学行为关系密切。STAT3,STAT5靶向治疗是目前肿瘤治疗领域研究的热点之一,并显示出良好的治疗前景。现就该方向研究的最新进展作一综述。
Aberrant expression and activation of STAT3 and STAT5 are closely related to tumorigenesis, development and malignant biological behaviors. Targeted therapy of STAT3 and STAT5 is one of the hot spots in the field of cancer therapy and shows a good therapeutic prospect. Now the direction of the latest research progress is reviewed.