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作者指出,接触石棉尘情况相似的人,发生石棉肺的严重性有所差异,这可能是机体具有某些因素改变了个体对吸入石棉尘的反应。这些因素中有一些可能与肺的免疫反应有关,因为发现石棉肺和煤尘肺病人体内抗核抗体(A.N.A)和类风湿因子有所增加。HL-A系统(人类白细胞抗原)是人体内主要的组织配合性抗原,与机体
The authors note that people with similar exposure to asbestos dust have different severity of asbestosis, which may be due to certain factors in the body that alter the individual’s response to inhaling asbestosis. Some of these factors may be related to the immune response to the lungs as there is an increase in A.N.A and rheumatoid factor found in asbestosis and pneumoconiosis patients. The HL-A system (human leukocyte antigen) is the major tissue-associated antigen in humans and interacts with the body