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目的 探讨非小细胞肺癌 (NSCLC)超分割 (HFX)放疗与CE方案化疗同步进行的疗效。方法 5 4例 (A组 )NSCLC患者行超分割放疗同步行CE静脉化疗 ,80例 (B组 )单纯超分割放疗。结果 A、B两组有效率分别为 88.9%、5 5 % ,A组明显高于B组 (P <0 .0 5 )。 1、2、3年生存率A、B两组分别为 66.7%、3 8.9%、18.5 % ;41.3 %、16.2 %、7.5 % (P <0 .0 5 )。中位生存期A组 14 .4个月 ,B组 10 .6个月。结论 超分割放疗同步CE方案治疗NSCLC可提高疗效 ,延长生存期。
Objective To investigate the curative effect of concurrent radiotherapy of non-small cell lung cancer (NSCLC) with chemotherapy regimen of CE. Methods Twenty-four patients (group A) with NSCLC underwent radical gastrectomy combined with venous thrombolysis and 80 patients (group B) with radical radiofrequency ablation. Results The effective rates of group A and group B were 88.9% and 55% respectively, while group A was significantly higher than group B (P <0.05). The 1-, 2- and 3-year survival rates were 66.7%, 8.9%, 18.5%, 41.3%, 16.2% and 7.5% in group A and B respectively (P <0.05). The median survival time was 14.4 months in A group and 10.6 months in B group. Conclusion Hyperfraction radiotherapy and concurrent CE regimen in the treatment of NSCLC can improve efficacy and prolong survival.