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目的观察腹腔镜联合药物治疗子宫内膜异位症合并不孕的临床疗效,为临床治疗子宫内膜异位症合并不孕提供参考。方法选取许昌市中医院2013年2月—2015年12月收治的73例子宫内膜异位症合并不孕患者,采用随机数字表法分为观察组(n=37)和对照组(n=36)。两组均给予腹腔镜手术治疗,观察组加用药物(孕三烯酮)治疗,疗程为3个月。比较两组3个月后的总有效率、6个月内的复发率、妊娠率。结果观察组总有效率为97.30%(36/37)高于对照组77.78%(28/36),差异有统计学意义(χ2=4.753,P<0.05);观察组6个月内复发率为2.70%(1/37),对照组8.33%(3/36),差异无统计学意义(χ2=0.294,P>0.05);观察组6个月内妊娠率为32.43%(12/37)高于对照组11.11%(4/36),差异有统计学意义(χ2=4.847,P<0.05)。结论腹腔镜联合药物治疗子宫内膜异位症合并不孕可提高患者妊娠率,改善患者临床症状。
Objective To observe the clinical efficacy of laparoscopy combined with drugs in the treatment of endometriosis complicated with infertility and provide reference for clinical treatment of endometriosis complicated with infertility. Methods Seventy-three patients with endometriosis complicated with infertility admitted to Xuchang Hospital of Traditional Chinese Medicine from February 2013 to December 2015 were randomly divided into observation group (n = 37) and control group (n = 36). Both groups were given laparoscopic surgery, the observation group plus drugs (gestrinone) treatment, treatment for 3 months. The total effective rate after 3 months, the recurrence rate within 6 months and the pregnancy rate were compared between the two groups. Results The total effective rate in the observation group was 97.30% (36/37), which was significantly higher than that in the control group (77.78%, 28/36) (χ2 = 4.753, P <0.05) 2.70% (1/37) in control group and 8.33% (3/36) in control group, the difference was not statistically significant (χ2 = 0.294, P> 0.05). The pregnancy rate in observation group within 6 months was 32.43% (12/37) In the control group, 11.11% (4/36), the difference was statistically significant (χ2 = 4.847, P <0.05). Conclusions Laparoscopy combined with drug treatment of endometriosis with infertility can improve the pregnancy rate and improve the clinical symptoms of patients.