论文部分内容阅读
目的研究认知行为疗法联合舍曲林治疗青少年强迫症的临床疗效。方法将符合入组标准的40例青少年强迫症患者随机分为两组,研究组(n=20):舍曲林合用认知行为治疗;对照组(n=20):单用舍曲林治疗。观察比较治疗4、8、12周后Yale-Brown强迫量表评分情况和临床疗效。结果 1治疗12周后研究组总有效率为75%,对照组总有效率为40%,两组间差异具有统计学意义(x2=5.013,P=0.025)。2研究组在治疗第4周末、8周末、12周末时,Yale-Brown强迫量表评分低于对照组,差异具有统计学意义(P<0.05)。3在治疗第4周末、8周末、12周末时,两组的副反应量表评分无显著差异(P>0.05)。结论认知治疗联用舍曲林能明显提高青少年强迫症患者的临床有效率,显著降低患者的强迫评分,改善临床症状。
Objective To study the clinical efficacy of cognitive behavioral therapy combined with sertraline in the treatment of adolescent obsessive-compulsive disorder. Methods 40 adolescents with obsessive-compulsive disorder who met the inclusion criteria were randomly divided into two groups: study group (n = 20): sertraline combined with cognitive behavioral therapy; control group (n = 20): sertraline alone . Observe and compare Yale-Brown Observe Scale and clinical curative effect after treatment for 4, 8 and 12 weeks. Results After treatment for 12 weeks, the total effective rate was 75% in the study group and 40% in the control group. The difference between the two groups was statistically significant (x2 = 5.013, P = 0.025). 2 The Yale-Brown Obsessive Compulsive Rating Scale was lower in the study group than in the control group at the 4th, 8th, and the 12th week of treatment. The difference was statistically significant (P <0.05). There was no significant difference (P> 0.05) between the two groups in the 4th, 8th, 12th week of treatment. Conclusion Cognitive therapy combined with sertraline can significantly improve the clinical efficacy of adolescent obsessive-compulsive disorder, significantly reduce the patient’s forced score and improve clinical symptoms.