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目的了解某市高考学生乙型肝炎病毒(HBV)感染情况,并分析HBV感染者的肝功能情况。为制定相应的防治策略提供科学依据。方法采用ELISA法检测我院2009年3883名高考体检学生的HBsAg和HBsAb,同时利用全自动生化分析仪检测血清丙氨酸氨基转移酶(ALT)。结果HBsAg阳性率为2.68%,男生与女生之间差异有统计学意义(P<0.01),其中男生为1.73%,女生为0.95%;未接种乙肝疫苗学生HBsAg阳性率高于接种疫苗者(P<0.01);ALT(ALT>40IU/L为异常),在所有体检学生中异常率为7.52%,男生与女生之间差异有统计学意义(P<0.01),男生为6.23%,女生为1.29%。结论对高中生应加强传染病相关知识的宣传,继续加强乙型肝炎疫苗的接种,预防HBV的传播。
Objective To understand the prevalence of hepatitis B virus (HBV) in college entrance examination in a city and to analyze the liver function of HBV infected persons. Provide a scientific basis for formulating the corresponding control strategy. Methods HBsAg and HBsAb in 3883 college entrance examination students in our hospital in 2009 were detected by ELISA. Serum alanine aminotransferase (ALT) was detected by automatic biochemical analyzer. Results The positive rate of HBsAg was 2.68%, there was a significant difference between boys and girls (P <0.01), which was 1.73% for boys and 0.95% for girls. The positive rate of HBsAg in non-vaccinated students was higher than that in vaccinated children <0.01). ALT (ALI> 40IU / L was abnormal). The abnormal rate of all students was 7.52%, there was a significant difference between male and female students (P <0.01) %. Conclusions The high school students should strengthen the publicity of relevant knowledge of infectious diseases and continue to strengthen the vaccination of hepatitis B vaccine to prevent the spread of HBV.