Identification of effective siRNA against K-ras in human pancreatic cancer cell line MiaPaCa-2 by si

• 作 者: WeiWang Chun-YouWang Ju-HuaDon
• 机 构: DepartmentofPancreasSurgeryCenter,DepartmentofCenterLab,DepartmentofENT,DepartmentofNeurology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2005年13期
• 关键词: SIRNA K-RAS 胰腺肿瘤 肿瘤细胞 MIAPACA-2 基因表达 K-ras RNAi siRNA siRNA expression casset

AIM: We shall construct the small interfering RNA (siRNA)expression cassette (SEC) targeting activated K-ras gene sequence, identify more effective siRNA sequence against K-ras gene in human pancreatic cancer cell line MiaPaCa-2 by SEC and reveal the anti