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目的:探讨中药治疗慢性阻塞性肺疾病(COPD)稳定期肺肾阴虚型患者的临床疗效及对肺功能影响。方法:将138例COPD稳定期肺肾阴虚患者随机分入对照组与治疗组,对照组患者接受常规西医治疗措施,治疗组患者在对照组治疗基础上加用补肺益阳化痰中药颗粒口服,疗程2个月。比较两组临床疗效、肺功能及生活质量的差别。结果:治疗组治疗总有效率显著高于对照组,差别具有统计学意义(95.7%vs 82.4%,P<0.05);治疗后治疗组肺功能指标用力肺活量(FVC)、第1秒用力肺活量占预计值百分比(FEV1)及FEV1/FVC显著优于对照组(P<0.05);治疗组健康状况调查问卷(SF-36)评分显著高于对照组(P<0.05)。结论:补肺益阳化痰中药可显著提高COPD稳定期肺肾阴虚患者临床疗效,并改善肺功能。
Objective: To investigate the clinical efficacy and the effect of traditional Chinese medicine (TCM) on lung function in patients with chronic obstructive pulmonary disease (COPD) at stable stage. Methods: 138 cases of stable COPD patients with lung and kidney yin deficiency were randomly divided into control group and treatment group. Patients in control group received routine Western medical treatment. Patients in treatment group received Bufei Yiyang Huatan Chinese medicine granules , Treatment for 2 months. The clinical efficacy, lung function and quality of life were compared between the two groups. Results: The total effective rate of the treatment group was significantly higher than that of the control group (95.7% vs 82.4%, P <0.05). After treatment, the FVC and FVC of the treatment group accounted for The predicted value of FEV1 and FEV1 / FVC were significantly better than those of the control group (P <0.05). SF-36 score of the treatment group was significantly higher than that of the control group (P <0.05). Conclusion: Bufei Yiyang Huatan Chinese medicine can significantly improve the clinical efficacy of COPD patients with stable stage of lung and kidney, and improve lung function.