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目的:探讨扶正芍药方加味与美沙拉嗪联用治疗溃疡性结肠炎的临床效果。方法:选取溃疡性结肠炎患者140例,采用随机数字表法分为对照组和观察组各70例,分别给予美沙拉嗪单用和与扶正芍药方加味联用治疗,比较两组患者临床疗效和治疗前后症状体征积分和结肠镜检积分。结果:观察组患者临床疗效显著优于对照组(P<0.05);两组患者治疗后症状体征积分和肠镜积分情况均较治疗前有明显改善((P<0.05));观察组患者治疗后症状体征积分和肠镜积分均显著低于对照组(P<0.05)。结论:扶正芍药方加味与美沙拉嗪联用治疗溃疡性结肠炎可显著改善临床症状,减轻肠道溃疡病变,具有临床应用价值。
Objective: To investigate the clinical effects of Fuzheng Shaoyao Fang flavored with mesalazine in the treatment of ulcerative colitis. Methods: A total of 140 patients with ulcerative colitis were selected and divided into control group and observation group by random number table. Each group was given Mesalazine alone and combined with Fuzheng Shaoyao Decoction. The clinical curative effect was compared between the two groups And before and after treatment of symptoms and signs score and colonoscopy score. Results: The clinical efficacy of the observation group was significantly better than that of the control group (P <0.05). The scores of symptom and sign and the score of colonoscopy in both groups were significantly improved after treatment (P <0.05) After symptom and symptom scores and colonoscopy scores were significantly lower than the control group (P <0.05). Conclusion: The combination of Fuzheng Shaoyao Fang and mesalazine for the treatment of ulcerative colitis can significantly improve the clinical symptoms and relieve the intestinal ulcer lesions, and has clinical value.