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目的:观察桂芍知母汤联合新型免疫抑制剂来氟米特治疗类风湿关节炎的临床疗效。方法:采取随机方法分治疗组和对照组,治疗组30例采用桂芍知母汤联合来氟米特治疗;对照组30例采用来氟米特配合传统免疫抑制剂治疗;两组常规应用非甾类消炎药。结果:治疗组近期控制率明显优于对照组(P<0.05),总有效率两组比较无显著差异(P>0.05)。结论:桂芍知母汤联合来氟米特治疗类风湿关节炎有较好的临床疗效,且毒副作用小,耐受性好,近期控制率明显优于对照组。
Objective: To observe the clinical efficacy of Guishao Zhimu Decoction combined with new immunosuppressant leflunomide in the treatment of rheumatoid arthritis. Methods: A randomized trial was divided into treatment group and control group. 30 cases in the treatment group were treated with Guizhu Zhimu Decoction combined with leflunomide, while 30 cases in the control group were treated with leflunomide and traditional immunosuppressive drugs. Two groups of conventional non-steroidal Anti-inflammatory drugs. Results: The recent control rate in the treatment group was significantly better than that in the control group (P <0.05). The total effective rate was no significant difference between the two groups (P> 0.05). Conclusion: Guizhao Zhimu Decoction combined with leflunomide treatment of rheumatoid arthritis has a better clinical efficacy, and side effects, tolerability is good, the recent control rate was significantly better than the control group.