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非小细胞肺癌(NSCLC)化疗失败的重要原因是由于肿瘤细胞具有耐药性,研究显示患者某些基因的表达水平直接影响化疗药物的疗效,DNA的损害及DNA修复能力的降低可增加多种肿瘤的遗传易感性。核苷酸切除修复系统
An important reason for the failure of chemotherapy for non-small cell lung cancer (NSCLC) is due to the tumor cells being resistant. Studies have shown that the expression level of some genes in patients directly affects the curative effect of chemotherapy drugs. The damage of DNA and the reduction of DNA repair ability can be increased The genetic predisposition of the tumor. Nucleotide excision repair system