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目的 :探讨跨声门癌局部浸润扩展的组织病理学特点及其临床意义。方法 :5 0例跨声门癌喉全切除标本制成连续切片 ,HE染色 ,光镜下观察。结果 :全部病例均系主体位于喉室或以喉室为中心。浸润方式以粘膜下深层浸润为主 ,占 90 % (45 / 5 0 )。跨声门癌向外早期侵入声门旁间隙 ,并沿该间隙以基本均等态式纵向跨区浸润扩展。结论 :跨声门癌原发喉室 ,其局部浸润扩展的组织病理学特点及临床表现均不同于其它类型喉癌 ,应列为单独一型。
Objective: To investigate the histopathological features and clinical significance of local infiltration expansion of transglottic cancer. Methods: Fifty cases of transglottic laryngectomy specimens were made into serial sections, HE staining and light microscopy. Results: All patients were mainly located in the throat or throat as the center. Infiltration mode to submucosal deep infiltration, accounting for 90% (45/50). Transglottic cancer invades the supraglottic space early outward and extends longitudinally across the region along the interspaces in a substantially uniform manner. CONCLUSIONS: The histologic features and clinical manifestations of transglottic cancer in the primary laryngeal cavity are different from those of other types of larynx and should be classified as single type.