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本文报道新生儿脐血和新生儿期、乳儿期等各阶段(共252例)的血清甲胎蛋白放射火箭电泳自显影测定的正常值(见表),并作初步讨论。胎儿出生后,甲胎蛋白即迅速减少。出生后1～5天,甲胎蛋白含量比脐血分别下降57.6％、58.1％、66.5％、68.3％、73.7％。出生后11～20天,甲胎蛋白值比脐带血下降98.3％,虽然随着年龄的增长,尤其在20天内甲胎蛋白含量急骤降低,但在3个月内并未完全消失,3个月以上至9足岁儿童甲胎蛋白含量均<31.5～31.5毫微克/毫升(在成人正常水平范围以内)。近年来,甲胎蛋白含量测定已被广泛应用于原发性肝细胞肝癌的辅助诊断,以及新生儿肝炎和胆道闭锁的鉴别
This article reports the normal values of neonatal umbilical cord blood, autoplasmy of neonatal and neonatal stages (252 cases in total) determined by autoradiography (see table), and makes a preliminary discussion. After the birth of the fetus, alpha-fetoprotein is rapidly reduced. From 1 to 5 days after birth, the alpha-fetoprotein content decreased by 57.6%, 58.1%, 66.5%, 68.3% and 73.7% respectively compared with cord blood. The alpha-fetoprotein value was 98.3% lower than that of cord blood at 11-20 days after birth, although the level of alpha-fetoprotein decreased sharply with age, especially within 20 days, but did not disappear completely within 3 months. After 3 months The alpha-fetoprotein content of children aged above 9 was <31.5-31.5 ng / mL (within adult normal range). In recent years, a-fetoprotein content determination has been widely used in the diagnosis of primary hepatocellular carcinoma, as well as the identification of neonatal hepatitis and biliary atresia