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延髓病变累及呼吸中枢时,可产生睡眠性呼吸暂停综合征(即:一次呼吸停止时间≥10秒,呼吸暂停—不全指数≥30.0).本文报告一例.患者,男、49岁,无高血压和肥胖史,患左侧Wallenberg’s综合征.五官科检查发现悬壅垂过长、鼻中隔歪曲阻塞左鼻孔.其妻提供无打鼾及睡眠呼吸暂停史.10天后吞咽困难缓解,但睡眠时出现严重打鼾和呼吸暂停.用多种描记仪行夜间呼吸监护,发现患者习惯仰卧、偶为右侧卧.测得平均每夜呼吸暂停和呼吸不全达150次,呼吸暂停—不全指数(apnea-hypopnea index)>30.0符合睡眠性呼吸暂停综合征之诊断.血氧饱和度有50次<85%,10次为80%.即氧分压(PaO_2)≤50mmHg.用一持续正压面罩给氧和纠正卧位后,呼吸暂停—不全指数降至7.0,呼吸暂停也明显改善.睡眠性呼吸暂停综合征分中枢型、梗阻型和混合型,常见于延髓梗塞,高位颈髓横贯性损害,橄榄桥脑小脑变性,多发性硬化,后脑畸形及延髓空洞症,延髓型脊髓髓灰质炎、外伤和新生物等.其
Medulla oblongata involving the respiratory center, can produce sleep apnea syndrome (ie, a breath stop time ≥ 10 seconds, apnea-insufficiency index ≥ 30.0.) This article reports a case of patients, male, 49 years old, no hypertension and Obesity history, suffering from left Wallenberg’s syndrome. ENT examination found that the suspension hanging too long, distorted nasal septum block the left nostril. His wife offers no snoring and sleep apnea history .10 days after swallowing difficulties, but sleep, severe snoring and Apnea-hypopnea index with nocturnal respiratory monitoring using a variety of tracings and found that the patient was supine, even for the right lateral .Abdominal apnea and hypopneas were measured for an average of 150 apnea-hypopnea indices> 30.0 meet the diagnosis of sleep apnea syndrome.Oxygen saturation 50 times <85%, 10 times 80% .Oxygen pressure (PaO_2) ≤50mmHg. With a continuous positive pressure mask to oxygen and to correct the supine position , Apnea - insufficiency index dropped to 7.0, apnea was also significantly improved.Sepam apnea syndrome in the central, obstructive and mixed type, common in the medullary infarction, high traumatic cervical spinal cord injury, olivopontocerebellar degeneration, Multiple Sclerosis, cerebral malformations and syringomyelia medulla oblongata, spinal bulbar polio, trauma and new biological its