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引起休克加重的因素有各种解释,如微循环异常、DIC、细胞代谢障碍和线粒体机能低下等。但一般认为休克是多脏器受损,休克患者的血中有多种特异性的物质,使休克加重。其中心肌抑制因子(MDF)和网状内皮抑制物质(RDS)乃属于这种物质。一、MDF:Lefer认为胰腺在缺血时有如下变化:①动脉压下降,血管弹性组织收缩;②交感神经紧张度增强,血管收缩;③血管紧张素Ⅱ、血管加压素等血管收缩物质产生和释放;④血小板聚集,形成
Factors that cause aggravating shock are various explanations, such as microcirculation abnormalities, DIC, cellular metabolic disorders and mitochondrial dysfunction. However, it is generally believed that shock is multiple organ damage, shock in patients with a variety of blood-specific substances that make the shock worse. Myocardial inhibitory factor (MDF) and reticuloendothelial inhibitory substances (RDS) belong to this substance. First, the MDF: Lefer that the pancreas in the ischemia have the following changes: ① arterial pressure, vascular elastic tissue contraction; ② sympathetic tone increased, vasoconstriction; ③ angiotensin Ⅱ, vasopressin and other vasoconstrictor substances And release; ④ platelet aggregation, the formation