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目的通过分析我院药房抗生素使用情况,提高抗生素用药的准确合理性。方法收集2015年1月至2016年3月于泰州市第二人民医院行非手术治疗的270患者的临床资料,调查分析包括抗生素使用种类、品种数、用药剂量、疗程、病原学送检情况等,计算患者抗菌药物使用率、使用抗生素治疗患者的病原学检测率、患者人均使用抗生素品种数、限定日剂量(DDD)、用药频度(DDDs)、使用强度(AUD)、平均用药时间等。结果我院住院药房抗生素使用率为57.9%,抗菌药物AUD平均为70(DDD/100人/d),治疗性使用抗菌药物住院患者病原学送检测率为41.9%;抗菌药物种类主要为头孢菌素类、喹诺酮类、青霉素类;头孢菌素类药物销售金额最高。结论医院抗菌药物使用率仍然较高,病原学检测率较低,抗生素种类选择较为集中,还需进一步对抗生素的应用进行管理。
Objective To analyze the use of antibiotics in pharmacies in our hospital to improve the accuracy and rationality of antibiotics. Methods The clinical data of 270 patients who were treated non-surgically in Taizhou Second People’s Hospital from January 2015 to March 2016 were collected. The investigation and analysis included the types of antibiotics used, number of varieties, dosage, course of treatment, etiological examination, etc. The antibiotic use rate, the etiological detection rate of antibiotics, the number of antibiotics per patient, DDD, DDDs, AUD, average medication time and so on were calculated. Results The hospital antibiotic use rate in hospital was 57.9%, the average antibacterial drug AUD was 70 (DDD / 100 persons / d), and the etiology of inpatients with therapeutic antibiotics was 41.9%. The main antibacterial drugs were cephalosporins Quinolones, penicillins; cephalosporins sales of the highest amount. Conclusion The utilization rate of antimicrobial drugs in hospitals is still high, the detection rate of pathogens is low, the selection of antibiotics is more concentrated, and further application of antibiotics is needed.