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本研究表明,茵栀保肝汤水煎浓缩液具有保护化学性肝损伤的作用,小鼠口服茵栀保肝汤25g/kg、75g/kg,能有效地降低CCl4引起的血清丙氨酸转氨酶(ALT)升高,使醋氨酚中毒的小鼠生存率达60%。大鼠口服茵栀保肝汤17g/kg、50g/kg,能降低血清ALT的活力和血清胆红素含量
This study shows that Yinzhi Baogan decoction concentrate has the effect of protecting chemical liver injury. The oral administration of Yinzhibaogan Decoction (25g/kg, 75g/kg) in mice can effectively reduce serum alanine aminotransferase (CAL) caused by CCl4 ( Increased ALT) increased the survival rate of acetaminophen-intoxicated mice by 60%. Oral administration of Yinqi Baogan decoction (17g/kg, 50g/kg) in rats can reduce serum ALT activity and serum bilirubin level