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一项有关PRODIGY研究的亚组分析显示,接受为期6个月及24个月双联抗血小板治疗(DAPT)的PCI后女性及男性患者2年时的缺血及出血结局相似。在PRODIGY研究中,男性受试者占23%。与男性相比,女性患者年龄更大、更容易合并ACS、高血压,肌酐清除率及CAD严重程度更低。研究者瑞士伯尔尼大学医院的Giuseppe Gargiulo及其同事对PRODIGY研究进行亚组分析,探讨与男性相比该研究中女性受试者的DAPT时程是否有所差异。结果发现,与6个月DAPT相比,24个月DAPT并不能
A subgroup analysis of the PRODIGY study showed similar outcomes for both women and men at 2 years of ischemia and bleeding after PCI for dual antiplatelet therapy (DAPT) for 6 months and 24 months. In the PRODIGY study, male subjects accounted for 23%. Women are older and more likely to have ACS, lower blood pressure, lower creatinine clearance, and lower CAD severity than men. Researchers Giuseppe Gargiulo and colleagues at the University Hospital Bern, Switzerland, conducted a subgroup analysis of the PRODIGY study to determine whether the DAPT duration of female subjects in this study was different from that of men. The results showed that, compared with 6 months DAPT, 24 months DAPT does not