经咽鼓管鼓室注入地塞米松治疗难治性突发性聋的临床观察

来源 :中国临床新医学 | 被引量 : 0次 | 上传用户:shaochao0926
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目的观察经咽鼓管鼓室内注入地塞米松对难治性突发性聋的治疗效果。方法对36例(36耳)常规治疗无效的突发性聋患者用电子喉镜经咽鼓管口逆向鼓室内注入地塞米松约5 mg,1次/2d,共5次。在治疗开始前1 d和治疗结束后3 d,分别测试受治疗耳的纯音听阈,比较受损频率纯音听阈均值(PTA),下降15 dB HL以上为有效。结果 36例经治患者20例有效,16例无效,有效率为55.56%。治疗前PTA为(71.63±10.60)dB HL,治疗后为(43.07±12.33)dB HL,治疗后比治疗前明显降低(P<0.05)。结论经咽鼓管逆行鼓室内注入地塞米松可作为常规治疗无效的突发性聋患者的再次挽救治疗的有效手段,也可以作为对激素治疗有禁忌证的突发性聋患者的治疗方法。 Objective To observe the therapeutic effect of dexamethasone injection on intractable sudden deafness via eustachian tube. Methods 36 cases (36 ears) of routine deafness patients with deafness were injected with dexamethasone about 5 mg once a day for 2 times through the eustachian tube through the eustachian tube for 5 times. At 1 d before treatment and 3 d after treatment, the pure tone hearing thresholds of the treated ears were measured, and the pure tone hearing threshold (PTA) of the lesion frequency was compared, and the decrease of more than 15 dB HL was effective. Results 36 cases were treated in 20 cases, 16 cases were ineffective, the effective rate was 55.56%. Before treatment, the PTA was (71.63 ± 10.60) dB HL, and was (43.07 ± 12.33) dB HL after treatment, which was significantly lower than that before treatment (P <0.05). Conclusion Intracranial intratympanic intratympanic intrathecal injection of dexamethasone can be used as a routine treatment of patients with sudden deafness to save again an effective means of treatment, but also as a contraindication for hormone therapy in patients with sudden deafness treatment.
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