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目的研究再次进行乳腺摄影筛查女性的特点和筛查结果。方法回顾性收集424703例连续的乳腺摄影筛查影像资料,以及发现乳腺癌的活检结果和手术报告。研究乳腺摄影情况,确定首次与二次检查是否存在相同的病变。结果总体的乳腺癌阳性预测值为38.6%(95%CI:37.3%～39.8%)。147例(2.6%)进行再次筛查的病人中,86例再次检查时存在不同的病变,其中32例为恶性(37.2%,95%CI:27.0%～47.4%)。61例女性再次检查的目的为相同病变,其中22例为恶性(36.1%,95%CI:24.1%～48.0%)。比较这些女性与首次乳腺摄影诊断为癌症的特点。与再次检查时相同病灶不为肿瘤者相比,患癌症者通常在乳腺摄影中表现为可疑高密度影(86.4%与53.8%,P=0.02),首次检查工作流程中的活检率较低(22.7%与61.5%,P=0.004)。结论对于再次进行乳腺筛查的女性,无论是由于相同病灶还是不同病灶而进行,再次筛查的恶性肿瘤风险与首次筛查者相当。
Objective To study the characteristics and screenings of women who have undergone mammography screening again. METHODS: A total of 424,703 consecutive mammographic screening images were retrospectively collected and biopsies and surgical reports of breast cancer were found. Study mammography, to determine whether the first and second check for the same lesions. Results The overall positive predictive value of breast cancer was 38.6% (95% CI: 37.3% -39.8%). Of the 147 patients (2.6%) who were re-screened, 86 had reexaminations with different lesions, of which 32 were malignant (37.2%, 95% CI: 27.0% to 47.4%). Sixty-one women were reexamined for the same disease, of which 22 were malignant (36.1%, 95% CI: 24.1% -48.0%). Comparison of these women with first breast mammography was diagnostic of cancer. Patients with cancer usually show suspiciously high intensity mammograms (86.4% vs. 53.8%, P = 0.02) compared with those with the same lesion as the tumor at reexamination, with a lower biopsy rate during the first check-up workflow 22.7% and 61.5%, P = 0.004). Conclusions For women who have undergone breast screening again, whether due to the same or a different lesion, the risk of re-screening of the malignancy is comparable to that of the first screening.