论文部分内容阅读
目的:探讨成人节细胞神经母细胞瘤的临床和病理特点。方法:回顾分析2例成人节细胞神经母细胞瘤的临床资料和病理资料。结果:2例均为体检时发现,无自觉症状,实验室检查均无异常。肿瘤大小分别为7cm× 5 cm和5 cm× 4 cm,包膜完整,均与周围组织有粘连,切面呈鱼肉状,免疫组化NSE,Syn,CgA,S-100及vi-mentin均为(+)。1例术后随访17个月死亡,1例随访6个月无转移。结论:成人节细胞神经母细胞瘤临床少见,多为体检时发现。治疗最有效的方法是手术切除,可辅以放、化疗。
Objective: To investigate the clinical and pathological features of adult ganglioneuroma neuroblastoma. Methods: The clinical data and pathological data of 2 adult ganglioneuroblastomas were retrospectively analyzed. Results: 2 cases were found during the physical examination, no symptoms, no abnormal laboratory tests. The tumor size was 7cm×5cm and 5cm×4cm, respectively. The capsules were intact. They all had adhesion to the surrounding tissues. The cut surface was fish-like. Immunohistochemical NSE, Syn, CgA, S-100 and vi-mentin were all ( +). One patient died after 17 months of follow-up. One patient was followed up for 6 months without metastasis. Conclusion: Adult ganglioneuroblastoma is rarely seen clinically. It is mostly found on physical examination. The most effective treatment is surgical resection, supplemented by radiotherapy and chemotherapy.