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电离辐射在人类致癌的证据首先得自早期使用放射仪器人员手部患非黑素瘤皮肤癌(NMSC)的报道。已注意到铀矿工人、放射工作者及童年因头癣或胸腺肥大接受X线治疗者患NMSC危险增加;NMSC是广岛、长崎原子弹爆炸所造成的最主要的癌症之一。本试验探讨放疗与基底细胞癌(BCC)及鳞状细胞癌(SCC)的相对危险性并评价这些危险与年龄及自初始治疗时间以及放疗时病情的关系。 病例为1980年1月至1986年2月被确诊的BCC或SCC患者,测试每天口服β-胡萝卜素是否可减轻
Evidence of ionizing radiation on human carcinogens was first reported in patients with non-melanoma skin cancer (NMSC) suffering from the early use of radiological equipment. It has been noted that uranium miners, radiologists and those who received X-ray therapy for head lice or thymus enlargement in their childhood have an increased risk of NMSC; NMSC is one of the most important cancers caused by the atomic bombing of Hiroshima and Nagasaki. This study investigated the relative risk of radiotherapy and basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) and evaluated the relationship between these risks and age and the time of initial treatment and radiotherapy. Patients with BCC or SCC who were diagnosed from January 1980 to February 1986 can test whether daily oral β-carotene can reduce