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目的分析2型糖尿病合并冠心病的危险因素及其与颈动脉及下肢动脉粥样硬化的相关性。方法将200例2型糖尿病患者分为冠心病组及非冠心病组,均接受颈动脉及下肢动脉血管彩超检查,并记录两组临床资料及实验室数据,分析冠心病的危险因素及与动脉粥样硬化的关系。结果①单因素分析发现年龄、病程、收缩压、总胆固醇、尿素氮、肌酐、尿微量白蛋白、24h尿总蛋白、高血压病史及脑梗死史,以及颈动脉、下肢动脉粥样硬化与糖尿病合并冠心病的发病呈正相关,P<0.05。②多因素分析提示颈动脉及下肢动脉粥样硬化是糖尿病合并冠心病的独立危险因素,其OR值分别为1.841(95%CI:1.117,3.033)和2.409(95%CI:1.659,3.497)。结论颈动脉及下肢动脉粥样硬化与2型糖尿病合并冠心病密切相关,其预测冠心病能力较传统危险因素强。
Objective To analyze the risk factors of type 2 diabetes complicated with coronary heart disease and its relationship with carotid and lower extremity atherosclerosis. Methods 200 patients with type 2 diabetes mellitus were divided into coronary heart disease group and non-coronary heart disease group. All patients underwent carotid artery and lower extremity arterial color Doppler ultrasound examination. The clinical data and laboratory data of two groups were recorded. The risk factors of coronary artery disease Atherosclerosis relationship. Results ① Univariate analysis showed that age, duration of disease, systolic blood pressure, total cholesterol, urea nitrogen, creatinine, urinary albumin, 24h urinary protein, history of hypertension and history of cerebral infarction, as well as atherosclerosis and diabetes mellitus The incidence of coronary heart disease was positively correlated, P <0.05. Multivariate analysis suggested that atherosclerosis of carotid and lower extremities was an independent risk factor for diabetes mellitus complicated with coronary heart disease. The OR values were 1.841 (95% CI: 1.117, 3.033) and 2.409 (95% CI: 1.659, 3.347), respectively. Conclusions Atherosclerosis of the carotid artery and lower extremity is closely related to type 2 diabetes mellitus with coronary heart disease, and its predictive ability of coronary heart disease is stronger than traditional risk factors.