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对55例长期接触实验性动物的过敏体质患者及70例健康对照者分别进行肺功能、气道反应性测定,同时记录接触动物时呼吸道症状的发生率。结果发现:对动物过敏原过敏的过敏体质患者较对照组FEV_1％显著降低,气道高反应性与呼吸道症状的发生率显著增高,提示长期接触实验性动物在过敏体质者较易出现气道高反应性及气流阻塞。
55 patients with long-term exposure to experimental animals and 70 healthy subjects with allergic patients were measured pulmonary function, airway responsiveness, while recording the incidence of respiratory symptoms when exposed to animals. The results showed that: allergic patients allergic to animal allergens than the control group FEV_1% significantly decreased airway hyperresponsiveness and respiratory symptoms were significantly increased, suggesting that long-term exposure to experimental animals in the allergy prone to airway height Reactivity and airflow obstruction.