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目的：探讨补充外源性谷氨酰胺（Ｇｌｎ）对运动机体抗氧化能力的影响。方法：采用大鼠力竭性游泳运动方式，通过补充Ｇｌｎ对比实验，观察力竭运动后１８小时大鼠肝组织中丙二醛（ＭＤＡ）、谷胱甘肽（ＧＳＨ）、超氧化物歧化酶（ＳＯＤ）含量的变化。结果：（１）肝组织ＭＤＡ含量单纯运动组显著高于安静对照组（Ｐ＜０．０１），补充Ｇｌｎ运动组变化不明显，补 充Ｇｌｎ运动组显著低于单纯运动组（Ｐ＜０．０１）。（２）单纯运动组肝组织ＧＳＨ含量显著低于安静对照组（Ｐ＜０．０１），补充Ｇｌｎ运动组显著高于单纯运动组（Ｐ＜０．０５）。（３）肝组织ＳＯＤ活力：单纯运动组显著高于安静对照组（Ｐ＜０．０５），补充Ｇｌｎ运动组变化不明显补充Ｇｌｎ运动组显著低于单纯运动组（Ｐ＜０．０１）。结论：补充外源性Ｇｌｎ有助于维持运动后肝组织中ＧＳＨ水平，增强其抗氧化损伤能力，减轻肝组织中的脂质过氧化反应
Objective: To investigate the effects of supplemental glutamine (Gln) on the anti-oxidative capacity of motor and body. Methods: By means of exhaustive swimming exercise in rats, glutamine (GSH), superoxide dismutase (SOD) content changes. Results: (1) The content of MDA in liver tissue of rats in exercise group was significantly higher than that in quiet exercise group (P <0.01), while the activity of Gln in exercise group was not significantly changed (P <0.01) ). (2) The content of GSH in liver tissue of exercise group was significantly lower than that in quiet control group (P <0.01). The Gln exercise group was significantly higher than that of simple exercise group (P <0.05). (3) The activity of SOD in the liver tissue in the exercise group was significantly higher than that in the quiet exercise group (P <0.05). The Gln exercise group was not significantly changed with Gln exercise group (P <0.01). Conclusion: Supplementation of exogenous Gln helps to maintain the level of GSH in the liver tissue after exercise, enhances its anti-oxidative damage ability and reduces the lipid peroxidation in liver tissue