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目的探讨缺血修饰蛋白(Ischemia modified albumin,IMA)在急性冠脉综合征(Acute coronary syndrome,ACS)早期诊断中的价值。方法选择以胸痛发作3h内急诊就诊的患者,通过白蛋白钴结合试验(ACB法)、免疫组化法分别检测患者的血清IMA、肌钙蛋白T(cTnT)及心电图,并与健康对照组比较,评价IMA对ACS的早期诊断价值。结果血清IMA、cTnT、ECG诊断ACS的敏感度分别为84.2%、32.6%、45.7%。结论 IMA可明显提高急性冠脉综合征早期诊断的敏感度。
Objective To investigate the value of Ischemia modified albumin (IMA) in the early diagnosis of acute coronary syndrome (ACS). Methods Patients with emergency treatment within 3 hours after onset of chest pain were enrolled in this study. Serum IMA, cTnT and ECG were detected by ACB method and immunohistochemistry respectively, and compared with healthy controls , Evaluate the value of IMA in the early diagnosis of ACS. Results The sensitivity of serum IMA, cTnT and ECG in diagnosing ACS was 84.2%, 32.6% and 45.7% respectively. Conclusion IMA can significantly improve the sensitivity of early diagnosis of acute coronary syndrome.