Effects of genistein on neuronal apoptosis, and expression of Bcl-2 and Bax proteins in the hippocam

• 作 者: Yun Peng Bo Jiang Huiling Wu R
• 机 构: DepartmentofNeurology,InstituteofEndocrinologyandMetabolism
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2012年36期
• 关键词: 神经细胞凋亡 BCL-2 海马神经元 蛋白表达 金雀异黄素 去卵巢大鼠 Bax 染料木素 ovariectomized model rats hippocamp
• 基金项目: supported by Hunan Provincial Traditional Medicine Administration Bureau,No.2010044

Genistein is one of several isoflavones that has a structure similar to 17β-estradiol, has a strong antioxidant effect, and a high affinity to estrogen receptors. At 15 weeks after ovariectomy, the expression of Bcl-2 in the hippocampus of rats decreased