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为了探讨清热止血药治疗乳糜尿机理,本组选择住院患者10例,经清热止血药治疗45夭,分别于治疗前后取材足背皮肤进行电镜比较观察。结果发现,治疗前破损严重的毛细淋巴管壁,治疗后修复完好;治疗前毛细血管内皮细胞的饮液小泡密集,治疗后明显减少;治疗前肥大细胞稀少而形态变异为梭形,治疗后明显增多,形态为圆形或椭圆形,核大,所含颗粒多而体积大;治疗前有淋巴水肿,治疗后消失。结果表明,淋巴管壁的广泛损伤为乳糜尿的发病机理,修复损伤管壁为其治疗机理。在修复过程中,肥大细胞可能具有工兵样作用。
In order to discuss the mechanism of the heat-clearing and hemostatic agents in the treatment of chyluria, 10 patients were hospitalized in this group and 45 patients were treated with a heat-quenching hemostatic agent. The skin of the foot was taken before and after treatment to compare the electron microscopy. The results showed that the severely damaged lymphatic wall before treatment was well repaired; after treatment, the capillary vesicles of the capillary endothelial cells were dense and decreased after treatment; the mast cells were sparse and the morphology was fusiform before treatment. Obvious increase, the shape of a round or oval, nuclear large, containing more and large particles; lymphadenopathy before treatment, disappear after treatment. The results showed that the extensive damage of the lymphatic vessel wall is the pathogenesis of chyluria, and repairing the damaged wall is the therapeutic mechanism. During repair, mast cells may have engineer-like effects.