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目的探讨早期药物治疗慢性呼吸衰竭合并肺性脑病的临床疗效。方法以景德镇市第一人民医院122例慢性呼吸衰竭合并肺性脑病患者为研究对象,对其进行分组治疗。对照组给予常规治疗,观察组在对照组的基础上,采用盐酸纳洛酮注射治疗。比较2组患者临床治疗效果。结果观察组总有效率为90.16%,对照组总有效率67.21%。2组比较,观察组总有效率高于对照组,差异具有统计学意义(P<0.05)。2组患者均未出现严重不良反应。结论盐酸纳洛酮注射治疗能够有效提高慢性呼吸衰竭合并肺性脑病的治疗效果,值得临床推广。
Objective To investigate the clinical effect of early drug treatment of chronic respiratory failure with pulmonary encephalopathy. Methods 122 patients with chronic respiratory failure and pulmonary encephalopathy in First People’s Hospital of Jingdezhen were studied and divided into groups. The control group was given routine treatment. The observation group was treated with naloxone hydrochloride injection on the basis of the control group. The clinical effects of two groups were compared. Results The total effective rate was 90.16% in the observation group and 67.21% in the control group. The total effective rate in observation group was higher than that in control group, the difference was statistically significant (P <0.05). Two groups of patients did not appear serious adverse reactions. Conclusion Naloxone hydrochloride injection can effectively improve the therapeutic effect of chronic respiratory failure combined with pulmonary encephalopathy, worthy of clinical promotion.