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月经血量可因宫内节育器(IUD)而增多,也可因服用避孕丸(BCP)而减少,故学者们推测BCP 可以抑制子宫内膜异位症的发展或防止其发生。作者就此进行前瞻性研究,以评价各种避孕方法与子宫内膜异位症的关系。在1985年10月至1986年12月间行腹腔镜输卵管绝育的566例患者中,于绝育前先行盆腔镜检,查出有典型棕色、黑色或蓝色病变伴周围纤维化的子宫内膜异位症42例,并与未避孕或用隔膜避孕者作对照。发现其各自的子宫内膜异位症发生率分别为:对照组7.6%,过去服用 BCP(1～15年)者6.3%,过去使用 IUD(1～6年)者为23.5%,过去合并使用 IUD 及 BCP者7.3%,现在仍用 BCP(1～9年)者5.9%,现在仍用 IUD(3～6年)者12.5%。经统计学处理后仅见过去用 IUD 者其子宫内膜异位症的发病率明显增高(P<0.0001),其余均无统计学意义。对于以上结果作者的解释是:周期性服用孕酮
The amount of menstrual blood can be increased by the IUD, but it can also be reduced by taking the BCP. Therefore, the authors speculate that BCP can inhibit the development of endometriosis or prevent its occurrence. The authors conducted a prospective study to evaluate the relationship between various contraceptive methods and endometriosis. Among the 566 patients undergoing laparoscopic tubal sterilization between October 1985 and December 1986, pelvic endoscopy was performed prior to sterilization to detect endometriosis with typical brown, black or blue lesions with peripheral fibrosis Symptoms in 42 cases, and with no contraception or contraceptive contraception as a control. The incidence of endometriosis was found to be 7.6% in the control group, 6.3% in the past for BCP (1-15 years) and 23.5% in the past for IUD (1-6 years), respectively 7.3% for IUD and BCP, 5.9% for BCP (1-9 years), and 12.5% for IUD (3-6 years). The incidence of endometriosis was only significantly increased (P <0.0001) after treatment with IUD only in the past, but the rest were not statistically significant. The author’s explanation for the above result is: Progesterone is taken periodically